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Y Chromosome Analysis

The test will show whether or not two men come from the same paternal line.

It is designed for comparing/identifying male descendants of a common male ancestor. The Y-chromosome DNA test is especially helpful in determining how closely two males may be related in a directly paternal lineage.

The Y Chromosome Analysis is used to measure the likelihood of paternally-linked relationships through different generations with a great degree of accuracy.

The cost of the test includes 2 men.

Additional individuals will be charged at the additional person rate specified.

The Y Chromosome test gives an accuracy of 99.999% for inclusions & 100% for exclusions.

Available as a Peace of Mind test only

Results available within 5-7 days of samples reaching our laboratories.

Express Services Available - click here

How does Y Chromosome Analysis work?

A chromosome is basically DNA that is coiled up very tightly.

The X and Y chromosomes determine the sex of an individual. Women have two X chromosomes and men have one X and one Y.

At conception a female child randomly receives a copy of either of her mothers X chromosomes and she also receives a copy the X chromsome belonging to her father.

A male child again randomly receives a copy either of his mothers X chromosome but this time receives a copy of the Y chromosome from the biological father.

The Y chromosome is passed on intact to male offspring and there is always only ONE Y chromosome to choose from (unlike the X chromosomes). This means that the Y chromosome passed on by a biological father to his son, is exactly the same (except for random mutation) as the Y chromosome he received from his father, who inturn received it from his father and so on and so on.

In addition, the Y chromosome of biological brothers, uncles and male cousins will also be identical.

The test analyses 11 genetic locations. Biologically related individuals should match BOTH alleles at all locations. This is different to the previous tests e.g. Paternity, which looks for a match of ONE allele at each location to the father and the a match of the second allele to the mother.

(When using non – sex chromosomes like those analysed in the other DNA tests performed, you would only expect to see both alleles match at all locations when looking at samples from identical twins.)

When should the test be used?

When all participants in a test are Male, this test may provide more information that the Sibling or Grand –parentage analysis – especially if there is a low participant number.

Case 1: Two men who believe they may be half or full Siblings/brothers.
Case 2: Grand – parent analysis, where a male child wants to test his PATERNAL grandparents (i.e. the parents of his biological father) This test would then compare the child’s Y chromosome with the Y chromosome of his potential grandfather.

What does the test show?

The test will show whether or not two men come from the same paternal line.

What does the test NOT show?

It will not give a conclusion on the nature of that Paternal relationship.

Case 1: In case 1 above, a positive result will demonstrate that the two men have a common paternal line, but it will not conclude that this is their biological father or that they are full or half Siblings. It will be for the Client to decide what the result means to them in the circumstances surrounding the test. However, if two men believe their only possible biological link to be their father, then this gives an excellent indication/level of evidence, that they have been fathered by the same person.

A negative result would demonstrate that they do not have a common paternal line and therefore can not have the same biological father.

Case 2: In case 2 above, a positive result will demonstrate that the two men have a common paternal line, but it will not conclude that they are grandfather and grandchild. It will be for the Client to decide what the result means to them in the circumstances surrounding the test. However, if two men believe their only possible biological link to be grandfather and grandchild, then this gives an excellent indication/level of evidence, that they are related in this way and that the grandfathers son is the biological father of the grandson.

A negative result would demonstrate that they do not have a common paternal line and therefore can not be paternally related.

When the test should not be used?

If women are involved in the test e.g. Sibling test for a potential brother and sister. Women do not possess Y chromosomes!

If all the participants are male but there is the possibility of another paternal link e.g. if the man being tested could either be a grand parent or second uncle to the child in question. This would occur if the potential fathers in a case were cousins!

Example of a result/conclusion statement for Y Chromosome Analysis.

STATEMENT

Y Chromosome analysis of BLANK and BLANK supports the hypothesis that BLANK and BLANK share a common paternal ancestor within a genealogically reasonable number of generations.

Y chromosome analysis of the individuals identified two distinct lineages. A comparison of the two haplotypes reveals that the individuals match all alleles identified.

 

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Our laboratory facilities are accredited by:

The United Kingdom Accreditation Service (UKAS) to the International Standard ISO 17025.

The Ministry of Justice to carry out parentage tests directed by civil courts in England and Wales under section 20 of the Family Law Reform Act 1969.

 


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